Best Anti-Inflammatory Supplements – What Experts Say

Overview

When the body reacts to stimuli such as infection, allergy, and injury, it gets inflamed. Inflammation may cause discomfort and pain. However, the body also needs inflammation to enhance wound healing and protect it from infections.

According to research in the Statpearls Journal, there are certain diseases associated with inflammation, including diabetes, arthritis, heart disease, Alzheimer’s disease, and other neurodegenerative diseases.

That is why you have the option of anti-inflammatory supplements. Anti-inflammatory supplements contain ingredients including curcumin, ginger root extract, bromelain, fish oil, vitamin D, green tea, cayenne pepper, and other potent ingredients. These ingredients work to improve inflammatory responses, reduce inflammations associated with certain conditions, boost immune functions, and support the functioning of other organs in the body.

These plant-based compounds generally work to reduce pains, swelling, and chronic or acute inflammations. A study published in the Surgical Neurology International journal by Joseph Maroon supports that anti-inflammatory supplements may reduce inflammatory pain and improve the quality of life. This is because they do contain ingredients like curcumin that have anti-inflammatory properties.

This article highlights some of the best anti-inflammatory supplements on the market today. We analyzed the ingredients in these supplements and the science behind them to ensure they are safe and effective. Join us as we explore the amazing benefits of these anti-inflammatory supplements.

How We Researched & Picked?

Before we chose the best anti-inflammatory dietary supplements on the market, we analyzed the composition of each supplement.

Ingredients – We specifically looked at the active ingredients in each supplement and the science that supports the effectiveness and safety of these ingredients.

Dosage – We were also very keen on the dosages of each supplement. We did this to make sure that all the ingredients in these supplements help reduce inflammation associated with certain chronic illnesses.

Free of additives – We did not choose any anti-inflammatory supplement that contains any harmful ingredients, including artificial preservatives, additives, colors, binders, and any other harmful chemicals. The inclusion of these ingredients may make people question the purity and safety of the supplements. These ingredients may also cause some adverse side effects.

Quality – It is key that we select high-quality products from top brands to ensure they truly support healthy inflammatory responses.

Best Anti-Inflammatory Supplements of 2025

Liposomal Curcumin – Overall Best

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*All the prices listed here are as they appear on their websites and are subject to change.

Our Rating

• Comfort 5/5
• Effectiveness 4.7/5
• Convenience 4.7/5
• Value 4.8/5

Amy Myers Liposomal Curcumin comes in liquid form and offers a form of curcumin that is highly absorbable and bioavailable. That is, the supplement is easily absorbed into the body and works to actively modulate a healthy inflammatory response.

The formula is a high-potent free radical fighter, which is what gives it special anti-inflammatory properties, with a score of 1500,000 oxygen radical absorbance capacity. This simply means it works fast to improve body discomfort.

Besides, Liposomal Curcumin has other benefits such as, it supports immune functions, improving liver and intestinal health, and improving gut lining.
The supplement is formulated by doctors, it is non-GMO, gluten-free, dairy free, and egg-free.

Key Specs

• Form: Liquid form
• Type: Anti-inflammatory supplement
• Brand: Amy Myers
• Benefit: Support normal immune functions, improve gut and intestinal health, improve inflammatory responses, and improve overall health.
• Active Ingredients: Liposomal curcumin, omega 9
• Dosage: 20ml daily
• Price: $34.97*

Pros & Cons of Liposomal Curcumin

Pros

• Liposomal Curcumin is formulated with no artificial sweeteners
• The supplement is made with natural and non-GMO ingredients
• The product is available in liquid form and is easily absorbed into the body
• It supports healthy inflammatory responses
• Has a great citrus flavor

Cons

• Individual results may vary
• Some people may not prefer liquid supplements

Natural Stacks – Best For Healthy Gut and Joints

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*All the prices listed here are as they appear on their websites and are subject to change.

Our Rating

• Comfort 3.9/5
• Effectiveness 4/5
• Convenience 3.9/5
• Value 3.8/5

Curcumin w/ Organic Coconut Oil offers a potent blend of health benefits in a convenient softgel form. Enhanced with NovaSOL® technology for superior absorption, this supplement is 185 times more bioavailable than regular curcumin powder. Ideal for supporting joint, brain, and cellular health, it’s a daily dose of wellness for your body and mind, presented in an easy-to-take and digestible format.

Key Specs

• Form: Softgel
• Type: Supplement
• Brand: Natural Stacks
• Benefit: Supports healthy joints, brain function, cellular function, and metabolism
• Ingredients: Curcumin Liquid Extract (NovaSOL®), Organic Coconut Oil
• Dosage: 2 softgels per day
• Price: $29.95*

Pros & Cons of Natural Stacks Turmeric Curcumin

Pros

• Highly bioavailable (185 times more than standard curcumin)
• Fast absorption due to NovaSOL® technology
• Contains healthy fats from organic coconut oil for enhanced absorption
• Supports multiple health aspects including joints, brain, and metabolism

Cons

• Higher price point compared to regular curcumin supplements
• Daily dosage of 2 softgels may not be convenient for all users
• Specific health benefits can vary between individuals

Turmeric Curcumin – Best Turmeric Curcumin Supplement with Black Pepper

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*All the prices listed here are as they appear on their websites and are subject to change.

Our Rating

• Comfort 3.7/5
• Effectiveness 3.8/5
• Convenience 3.8/5
• Value 3.7/5

Nature’s Nutrition presents Turmeric Curcumin 2600mg with Black Pepper, a potent herbal supplement designed for natural joint support. Infused with 95% standardized curcuminoids and BioPerine for enhanced absorption, this supplement harnesses the anti-inflammatory and antioxidant powers of turmeric in a convenient capsule form.

Key Specs

• Form: Capsules
• Type: Herbal Supplement
• Brand: Nature’s Nutrition
• Benefit: Supports healthy joints, brain function, cellular function, and metabolism
• Ingredients: Curcumin Liquid Extract (NovaSOL®), Organic Coconut Oil
• Dosage: 4 capsules per day
• Price: $21.62*

Pros & Cons of Thorne Curcumin Phytosome

Pros

• High potency
• Enhanced absorption with BioPerine
• Natural ingredients

Cons

• May not be suitable for individuals with certain medical conditions
• Relatively high price point

Thorne Curcumin Phytosome – Best Supplement For Healthy Inflammatory

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*All the prices listed here are as they appear on their websites and are subject to change.

Our Rating

• Comfort 3.7/5
• Effectiveness 3.8/5
• Convenience 3.8/5
• Value 3.7/5

Thorne’s Curcumin Phytosome offers a new take on traditional turmeric supplements. Utilizing advanced phytosome technology for enhanced absorption, it delivers potent antioxidant and anti-inflammatory benefits. Ideal for those seeking natural relief from joint and muscle soreness, it’s an innovative approach to holistic health.

Key Specs

• Form: Capsules
• Type: Herbal Supplement
• Brand: Thorne
• Benefit: Supports joint and muscle health, potent antioxidant, enhanced absorption
• Ingredients: Curcumin Phytosome (Meriva), Phospholipids from Sunflower Oil
• Dosage: 1-2 capsules two times daily
• Price: $45.00*

Pros & Cons of Thorne Curcumin Phytosome

Pros

• Highly absorbed formula with phytosome technology
• Addresses joint stiffness and muscle soreness
• Dairy, gluten, and soy-free

Cons

• Higher cost compared to other curcumin supplements
• May require consistent usage for best results
• Not suitable for individuals with certain allergies

Vimerson Health – Best Anti Inflammatory Supplements For Joint Health

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*All the prices listed here are as they appear on their websites and are subject to change.

Our Rating

• Comfort 3.6/5
• Effectiveness 3.7/5
• Convenience 3.6/5
• Value 3.6/5

Vimerson Health’s Glucosamine Chondroitin Supplement is a blend of natural ingredients designed to support joint health and flexibility. With key components like Glucosamine, Chondroitin, Turmeric, and MSM, it’s formulated to aid in easing joint discomfort and promoting overall joint mobility, making it a go-to choice for maintaining an active lifestyle.

Key Specs

• Form: Capsules
• Type: Herbal Supplement
• Brand: Vimerson Health
• Benefit: Supports joint health, flexibility, and mobility
• Ingredients: Glucosamine Sulfate, Chondroitin, Turmeric, MSM, Boswellia Extract, Quercetin, L-Methionine, Bromelain
• Dosage: 3 capsules per day
• Price: $28.97*

Pros & Cons of Vimerson Health

Pros

• Comprehensive blend of joint-supporting ingredients
• Non-GMO, dairy-free, gluten-free, and soy-free
• Formulated to support joint flexibility and mobility

Cons

• Dosage of 3 capsules per day might be high for some users
• May require continuous use for noticeable effects
• Price may be a consideration for regular use

Key Ingredients To Look For in Best Anti-Inflammatory Supplements

Ashwagandha

Ashwagandha is a traditional herb used for many years because of its therapeutic and medicinal properties. Ashwagandha may boost energy levels, increase focus and concentration, relieve stress, and improve athletic performance. Ashwagandha may also regulate blood sugar levels, improve cognitive health, and improve sleep.

Additionally, Ashwagandha contains active compounds that help improve inflammatory responses in humans.

According to research done by Paulina Mikulska and published in the Pharmaceutical Journal, Ashwagandha has certain health-promoting benefits. This includes anti-diabetic, antimicrobial, and cardio-protective effects. The study further supports that Withania somnifera has anti-inflammatory properties to help reduce inflammatory markers in the body.

Ginger Root Extract

Ginger root contains gingerol as its bioactive compound. Gingerol contains anti-inflammatory properties to help manage conditions like arthritis, reduce menstrual cramps, and improve symptoms of joint degenerative diseases. Ginger root may also reduce the risk of heart diseases, lower blood sugar levels, lower cholesterol levels, and treat chronic indigestion.

A publication in the National Library of Medicine by Morni Modi reveals that ginger root has nutritional properties and may help in the treatment of certain conditions. It supports that ginger is high in polyphenols and gingerols to help calm inflammation in the gastrointestinal tract. It is also rich in vitamins and micronutrients that prevent certain diseases.

Cinnamon Bark

Cinnamon is included in dietary supplements because of its wide range of health benefits. Cinnamon contains calcium, magnesium, and potassium to help support nerve functions, regulate blood pressure levels, improve bone health, and improve gastrointestinal health. Cinnamon also has antioxidant and anti-inflammatory effects to help neutralize free radicals and fight inflammation.

The Evidence-Based Complementary and Alternative Medicine journal by Pasupuleti Visweswara Rao reveals that cinnamon contains vital oils that have lipid-lowering, anticancer, antidiabetic, anti-microbial, antioxidant, and anti-inflammatory effects. It may also reduce the risk of cardiovascular diseases.

Omega 3 Fish Oil

Omega 3 fish oil contains essential nutrients that help support the development of the brain, improve vessel function, influence gene expression, and support blood clotting. Research studies support that omega-3 fatty acids may help reduce inflammation in people with arthritis. It helps in the management of blood pressure levels, reduces the risk of heart disease, and improves cognitive health.

According to the Journal of Biochemical Society Transactions by Philip Calder, omega-3 supplements contain EPA and DHA, which have anti-inflammatory properties to improve inflammatory responses in humans. Patients who take omega-3 supplements report reduced inflammation in their conditions.

Turmeric

Turmeric contains curcumin, a bioactive compound that has antioxidant and anti-inflammatory properties. Curcumin may lower inflammation in certain chronic conditions like metabolic syndrome, cancer, heart disease, and other degenerative conditions.

Curcumin may boost brain functions, neutralize free radicals, fight anxiety and depression, and delay the aging process.

According to research published in the Herbal Medicine Biomolecular and Clinical Aspects journal by Sahdeo Prasad, turmeric spice has antimicrobial, antioxidant, and anti-inflammatory properties. Turmeric may also relieve arthritis, improve digestion, relieve stomach gas, and enhance wound healing.

Key Mistakes to Avoid When Choosing Anti-Inflammatory Supplements

• Ignoring the Ingredients – It is very important that you look at the ingredients in the supplements and their nutritional value before you make your purchases. A publication in the Nutrients Journal supports that vitamin C, E, and unsaturated fatty acids are some key ingredients to look out for in anti-inflammatory supplements.^[1] Choose products from brands that do not include harmful substances in their formulations.
• Not Considering Your Actual Needs – You need to know what anti-inflammatory supplements are before you start using them. If you constantly suffer from inflammation or you have a condition that is associated with inflammation, then you should try anti-inflammatory supplements.
• Ignoring the Brand’s Reputation – The brand is an important aspect to consider when it comes to choosing dietary supplements. In selecting our top anti-inflammatory supplements, we shoes from reputable and trusted brands on the market.
• Not Being Keen on Reviews – You should also select products that have positive customer reviews from real people who have tried the product. With this, you can be sure to trust the supplement.

Final Verdict

Anti-inflammatory supplements are marketed for their pain and inflammation relief benefits. They do contain plant compounds with active ingredients that work to calm inflammation associated with certain conditions like gut inflammation, arthritis, diabetes, and cardiovascular diseases.

There are many anti-inflammatory supplements on the market today and picking the best one may pose a challenge. But don’t worry, we have done the hard work of researching and identifying the best anti-inflammatory supplements available on the market today.

We have chosen products with high-quality ingredients to ensure they deliver optimum results. With the list we have offered above, you are better placed to start your pain-free life with products that at least have been expertly selected and so you are likely to see better results, faster.

RELATED ARTICLE – The 7 Best Turmeric Curcumin Supplements of 2025, According to a Dietitian

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