7 Best Supplements For Nerve Pain: Experts Recommended

Neuropathy is a common condition that affects many individuals globally. Neuropathy may be associated with conditions like physical injury, diabetes, alcohol dependency, chemotherapy, and multiple sclerosis.

Nerve conditions cause a certain kind of discomfort that may affect mobility, daily activities, and sleep quality.

Luckily, there are various methods available to help relieve nerve pains, inflammation, and discomfort. Individuals may resort to acupuncture, physical rehabilitation, over-the-counter medications, and dietary supplementation.

Nerve dietary supplements work to ensure optimum functioning of the nervous system. The supplements may relieve nerve pain, reduce inflammation, mitigate symptoms associated with neuropathy, enhance muscular regeneration, and improve mobility.

Additionally, incorporating nerve supplements in your diet may help improve blood circulation to organs, reduce stress and anxiety, promote quality sleep, and slow down diabetic neuropathy.

Researchers Tina Okdahi and Christina Brook in a study shared in the Current Diabetes Reports Journal support the potential effectiveness of nerve supplements.

This is because they contain high-quality ingredients like marshmallow root, B vitamins, alpha lipoic acid, skullcap extract, vitamin D, and passion flower herb among many others. The micro-nutrients and essential vitamins in these supplements offer additional benefits beyond supporting nerve health.

In this article, we have done a detailed analysis of some of the best nerve supplements on the market. We have reviewed the ingredients and the science supports their effectiveness. It is time you enjoy the transformative benefits of nerve supplements.

How We Researched & Picked?

Since the market is full of numerous products, we selected the best nerve supplements by carefully analyzing the product ingredients and the dosage.

We also verified the effectiveness and safety of these ingredients through scientific research and clinical trials. We did this to ensure that people use products with ingredients that support optimal nerve functions.

Our choices do not include products that harmful substances and chemicals in their formulations. We eliminated nerve supplements that contain artificial flavors, colors, binders, additives, and other chemicals that may cause harm or adverse side effects to the body.

It is essential to us that clients are happy with the choices they make because of the transformative results they receive. That is why we only pick high-quality products from trusted manufacturers.

Best Nerve Supplements of 2025

NervoLink – Best Supplements for Nerve Health

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*All the prices listed here are as they appear on their websites and are subject to change.

Our Rating

• Comfort 4.9/5
• Effectiveness 4.9/5
• Convenience 4.9/5
• Value 4.8/5

NervoLink harnesses the power of natural ingredients like Cordyceps Sinensis and a blend of mushrooms to support healthy nerves. It’s a natural choice for anyone looking to maintain nerve health in their arms and feet, blending traditional ingredients with modern wellness.

Key Specs

• Form: Capsules
• Type: Supplement
• Brand: NervoLink
• Benefit: Supports nerve health in arms and feet
• Ingredients: Cordyceps Sinensis Powder, Reishi, Shiitake, Maitake Mushrooms, Lion’s Mane, Turkey Tail, Royal Sun Agaricus, White Button Mushroom, Black Fungus
• Dosage: 2 capsules daily
• Price: $69.00*

Pros & Cons of NervoLink

Pros

• Natural blend of mushrooms and herbs
• Focuses on nerve health in arms and feet
• Non-GMO, free from harmful stimulants and toxins

Cons

• Higher price point for a 30-day supply
• Lack of specific dosage information
• Results may vary among individuals

Nervogen Pro – Best Supplements For Neuropathy

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*All the prices listed here are as they appear on their websites and are subject to change.

Our Rating

• Comfort 4.7/5
• Effectiveness 4.8/5
• Convenience 4.8/5
• Value 4.8/5

Nervogen Pro harnesses the power of natural ingredients like Cordyceps Sinensis and a blend of mushrooms to support healthy nerves. It’s a natural choice for anyone looking to maintain nerve health in their arms and feet, blending traditional ingredients with modern wellness.

Key Specs

• Form: Capsules
• Type: Supplement
• Brand: Nervogen Pro
• Benefit: Supports nerve health, provides relief from nerve discomfort
• Ingredients: Passiflora Incarnate, Corydalis Yanhuosuo, California Poppy Seeds, Prickly Pear, Marshmallow Root
• Dosage: 2 capsules daily
• Price: $69.00*

Pros & Cons of Nervogen Pro

Pros

• Unique blend of traditional ingredients
• Focused on nerve health and discomfort relief
• Natural formulation

Cons

• Relatively high cost per bottle
• Dosage information is not clear
• Results may vary from person to person

Nerve Renew – Best Nerve Support Supplements

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*All the prices listed here are as they appear on their websites and are subject to change.

Our Rating

• Comfort 4.9/5
• Effectiveness 4.9/5
• Convenience 4.9/5
• Value 4.8/5

Nerve Renew is a line of product that uses blended formula and science-backed combination of vitamins, antioxidants, and herbs to promote healthy nerve function and other health related benefits.

Key Specs

• Form: Capsules
• Type: Supplement
• Brand: Nerve Renew
• Benefit: Builds nerve insulation, nourishes nerves, promotes blood flow & oxygen to the nerves
• Ingredients: Tribulus Terrestris, saw palmetto, Damiana, Hawthorn berry extract, Catuaba bark extract, Ginkgo biloba, Muira puama bark extract
• Dosage: 2 capsules daily
• Price: $69.00*

Pros & Cons of Nerve Renew

Pros

• The products support healthy nerve function
• They purport to also support proper circulation of blood and dilation of blood vessels
• Aid in restorative sleep and total body relaxation
• Improves energy and mental clarity
• Reduce stress and anxiety

Cons

• There is no free trial offer
• Products are available online

Premier Vitality NeuroPure – Best Supplements for Neuropathy

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*All the prices listed here are as they appear on their websites and are subject to change.

Our Rating

• Comfort 4.8/5
• Effectiveness 5/5
• Convenience 4.8/5
• Value 4.9/5

Premier Vitality NeuroPure is a dietary supplement meticulously formulated to aid in the support of nerve health and mitigate symptoms associated with neuropathy. It uses natural, high-quality ingredients to help ease neuropathy symptoms which supports nerve health and overall well-being.

Key Specs

• Form: Capsules
• Type: Supplement
• Benefit: Supports nerve function, improves sleep, eases nerve pain, boosts energy levels, balances blood sugar, improves health, strengthens the immune system
• Brand: Premier Vitality
• Active Ingredients: Prickly Pear, Passionflower, California Poppy, Marshmallow Root, Corydalis
• Dosage: 2 capsules daily
• Price: $69.00*

Premier Vitality NeuroPure Pros & Cons

Pros

• Supports nerve health and decreases pain 
• Non-GMO, gluten-free, and free from artificial preservatives
• Manufactured in an FDA-registered facility
• Each ingredient is backed by research

Cons

• You can only purchase NeuroPure online
• The results may vary for different customers
• High demand may lead to low stock at times

ProNerve6 – Best Nerve Health Supplements

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*All the prices listed here are as they appear on their websites and are subject to change.

Our Rating

• Comfort 4.8/5
• Effectiveness 4.9/5
• Convenience 4.8/5
• Value 4.8/5

ProNerve6 is a natural supplement designed to support central nervous system health. With ingredients like licorice root, vitamin C, cinnamon bark, and alpha-lipoic acid, it helps ease nerve pain, provides antioxidant support, and improves nerve health. It’s vegan-friendly with gelatin-free capsules.

Key Specs

• Form: Capsules
• Type: Supplement
• Benefits: Alleviates nerve pain, Promotes Healthy Brain Function and Provides Antioxidant Support
• Brand: ProNerve6
• Active Ingredients: Licorice root powder, vitamin C, cinnamon bark powder, alpha lipoic acid
• Dosage: 2 capsules 20-30 minutes before their largest meal
• Price: $69.00*

Pros & Cons of ProNerve6

Pros

• Alleviates Nerve Pain
• Beneficial for Joint Health
• Good Customer Reviews
• Gluten-Free
• Supports Healthy Organ Function

Cons

• Limited Availability
• Result Times May Vary

Nerve Control 911 – Best Supplement for Central Nervous System

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*All the prices listed here are as they appear on their websites and are subject to change.

Our Rating

• Comfort 5/5
• Effectiveness 5/5
• Convenience 5/5
• Value 4.9/5

Nerve Control 911 is a nutritional supplement that supports optimal functioning of the nervous system. The supplement is made with quality ingredients and herbal extracts which helps to reduce nerve pain, improve circulation, enhance muscle function, and support vision, making it suitable for both men and women.

Key Specs

• Form: Capsules
• Type: Dietary supplement
• Brand: PhytAge Labs
• Benefit: Alleviates neuropathic pains, enhances muscular functions, regulates motor skills, and supports healthy reflexes.
• Active Ingredients: Marshmallow root, prickly pear, passion flower herb, California poppy seed
• Dosage: Two capsules every day
• Return Policy: 90-day money-back guarantee
• Price: $69.95*

Pros & Cons of Nerve Control 911

Pros

• Promotes optimal nerve functions
• Reduces nerve pain and inflammation
• It includes plant-based and natural ingredients
• Ideal for men and women

Cons

• Individual results may vary

BioMed Nutrition NeuroGen – Best Supplement For Brain and Nerve Function

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*All the prices listed here are as they appear on their websites and are subject to change.

Our Rating

• Comfort 3.9/5
• Effectiveness 4/5
• Convenience 3.9/5
• Value 3.8/5

BioMed Nutrition’s NeuroGen is a comprehensive supplement designed for nerve support, offering a natural approach to managing nerve-related issues. Incorporating a rich blend of ingredients like Acetyl L-Carnitine, Benfotiamine, and Curcumin, it targets nerve health, aiming to alleviate discomfort and improve function.

Key Specs

• Form: Capsules
• Type: Supplement
• Brand: BioMed Nutrition
• Benefit: Improves nerve function, decreases nerve pain, supports nerve regeneration
• Ingredients: Acetyl L-Carnitine, Benfotiamine, Bioperine, Bromelain, Coenzyme Q-10, Curcumin, Methylcobalamin, N-Acetyl Cysteine, R-Alpha Lipoic Acid, Serrapeptase, Vitamin B6, Vitamin D3
• Dosage: 3 capsules two times per day between meals
• Price: $79.99*

Pros & Cons of NeuroGen

Pros

• Comprehensive blend of active ingredients for nerve support
• Targets various aspects of nerve health including pain relief and regeneration
• Free from harmful stimulants and toxins

Cons

• High price point for a single bottle

What is Neuropathy?

Neuropathy affects the nerves that connect your brain and spinal cord to the rest of your body. These nerves act as your body’s communication network, helping you feel sensations and control your movements. When this network gets damaged, it can cause chronic pain and even loss of coordination.

Many health issues can lead to neuropathy, including diabetes, lupus, arthritis, and Lyme disease. Even something as common as carpal tunnel syndrome can cause nerve damage*.^[1]

You may experience the following sensations:

• Pain or burning sensations
• Numbness in your hands and feet
• Tingling feelings
• Muscle weakness
• Painful cramps

Catching neuropathy early makes a big difference. Quick treatment can help prevent more nerve damage and keep your symptoms under control.

If you notice any unusual sensations, especially in your hands or feet, talk to your doctor. They can help find the cause and create a plan to protect your nerves.

Different Types of Neuropathy

Neuropathy comes in two main types, depending on whether it affects one nerve or many nerves. Understanding which type you have helps guide your treatment.

1. Mononeuropathy (When One Nerve Hurts): Mononeuropathy affects a single nerve in your body, usually one that sits close to your skin or near a bone. Think of it like a single electrical wire getting pinched or damaged. The most common example is carpal tunnel syndrome, which affects the nerve in your wrist*.^[2]

Common signs include:

• Numbness in specific areas
• Weakness where the nerve runs
• Burning pain or “pins and needles” feeling

This nerve problem can happen to anyone, but people with diabetes face a higher risk. Several things can cause it:

• Pressure from staying in one position too long
• Injuries or swelling
• Repetitive motions
• Poorly fitted casts or crutches

Early treatment helps prevent long-term problems. Your doctor might suggest relieving pressure on the nerve, trying steroid shots, wearing a splint, or sometimes surgery. Remember, quick action helps avoid lasting damage, so see your doctor if you notice any unusual nerve symptoms.^[2]

2. Polyneuropathy (When Many Nerves Are Affected): Polyneuropathy happens when nerve damage affects multiple nerves throughout your body. Unlike damage to a single nerve, this condition impacts how you move and feel in different areas. Think of it as multiple electrical circuits in your body experiencing problems at once.^[3]

Common Causes of Polyneuropathy:

• Diabetes
• Long-term alcohol use
• Vitamin deficiencies
• Certain medications
• Autoimmune disorders
• Poor blood circulation

Signs You Might Notice: You might notice several signs, such as numbness or tingling starting in the toes and fingers, muscle weakness, and problems with balance. You may also experience difficulty walking, burning pain, and changes in how you perceive temperature or touch. These symptoms can indicate underlying nerve-related issues.

Early treatment makes a big difference. Your doctor can help find the cause and create a treatment plan that might include medications, physical therapy, or lifestyle changes. While some people recover fully with proper care, others might need ongoing support to manage their symptoms.^[3]

How It Affects You: Different nerves control different functions in your body such as

• Movement nerves affect your muscle strength and coordination
• Feeling nerves affect your sense of touch and balance
• Body function nerves affect things like heart rate, sweating, and digestion

Each person’s experience is unique. Some people feel mild symptoms that come and go, while others might have more severe, ongoing challenges. Understanding which type you have helps your doctor create the right treatment plan for you.

Key Ingredients To Look For in Nerve Supplements

Alpha Lipoic Acid

Alpha lipoic acid is found in different cells in the body as it helps in the conversion of blood sugar into energy. Research studies support that alpha lipoic acid may help lower blood sugar levels in people with diabetes.It also works as an antioxidant to help neutralize free radicals and prevent cellular damage. Alpha lipoic acid improves conditions like diabetic peripheral neuropathy, improve insulin resistance, and improve nerve functions.

In one of the research done by Hiep Guyen and published in the National Library of Medicine, alpha lipoic acid is used in the treatment and management of oxidative stress-related diseases. As an antioxidant, alpha lipoic acid helps slow down metabolic syndrome and manage diabetic neuropathy.^[4]

Vitamins

B vitamins are essential because they help convert the food we eat into energy for the body. Adequate amounts of B vitamins reduce the risk of anemia by increasing the formation of red blood cells. Vitamins B1, B6, and B12 are referred to as neurotropic vitamins because they support a healthy nervous system. Vitamin B1 nourishes the nerves, vitamin B6 supports nerve communication, and vitamin B12 supports the formation of red blood cells and nerve cells.

According to research done by Carlos Alberto Calderon Espina and published in the Neuroscience and Therapeutics journal, B vitamins play a crucial role in supporting the functioning of the nervous system.^[5]

Omega 3 Fatty Acids

Recent research supports that omega-3 fatty acids may help protect the nerves against damage and enhance nerve recovery after an injury occurs. Omega 3 fatty acids may also help reduce pain and inflammation in the nerves, reduce oxidative stress, and manage neuroinflammation. Additionally, omega-3 fatty acids may improve sensorimotor functions in people who have had spinal cord injuries.

A publication in the Neuromolecular Medicine journal by S C Dyall reveals that polyunsaturated fatty acids like omega 3 and omega 6 are essential in the functioning of the central nervous system. The study further supports that adequate omega-3 fatty acids support nerve development and improve visual function.^[6]

Skullcap Extract

Skullcap is a flowering plant that is included in supplements, which may help reduce inflammation, improve mood, and reduce the effects of some types of cancers. Skullcap has anti-inflammatory properties; it may reduce stress and anxiety, improve sleep quality, and reduce damage associated with heart attacks. Additionally, the skullcap protects the body against neurodegenerative diseases.

A study published in the Journal of Brain Sciences by Kandhasamy claims that neurodegenerative diseases often cause the loss of neurons. The study concluded that neuroprotective agents, including the use of skullcap supplements, may help stimulate neurogenesis, reduce inflammation and oxidative stress, and enhance cognitive functions.^[7]

Marshmallow Root

The healing properties of the marshmallow root make it a common ingredient in dietary supplements. The powerful plant extract may help in the treatment of colds and coughs, relieve skin irritation, enhance wound healing, and relieve pain and inflammation. Marshmallow root may also improve digestion, support heart health, and soothe the nerve-sense system.

According to research published in the Antioxidants Journal by Sameh Zaghlool, herbal/medicinal plant extracts like the marshmallow root have therapeutic benefits to the body.^[8] Marshmallow root is a powerful anti-inflammatory and antioxidant extract that may treat gastrointestinal disorders.

Medical Treatments for Neuropathy

Your doctor can offer several treatment options for neuropathy, each tailored to what’s causing your nerve pain. Here’s how medical treatments can help:

Pain Management: Start with over-the-counter pain relievers like acetaminophen or ibuprofen for mild discomfort*.^[9] Your doctor might prescribe stronger medications like anticonvulsants or antidepressants for more severe nerve pain. Special creams and patches can also target specific painful areas*.^[10]

Treating Root Causes: Your doctor will help you manage underlying conditions. For diabetes, this means controlling blood sugar through medication and lifestyle changes. If infections or immune system problems cause your neuropathy, you might need specific medications to address these issues.

Specialized Therapies: TENS therapy uses gentle electrical currents to ease your pain. In more serious cases, treatments like plasma exchange or immune therapy can help your body heal.^[10]

Support and Movement: Physical therapy helps you stay strong and steady on your feet. Simple aids like comfortable shoes or supportive braces can make daily activities easier and protect your feet from injury*.

Early diagnosis and treatment are essential, and supplements may help reduce discomfort while avoiding expensive treatments.

Natural Remedies for Neuropathy

Beyond medications, you can take several natural approaches to manage neuropathy and improve your daily comfort. Here’s how you can help your body heal:

Lifestyle Changes: Your daily habits make a big difference. Stop smoking, limit alcohol, and stay active with regular exercise. Keeping a healthy weight also helps reduce pressure on your nerves.

Mind-Body Techniques: Give your mind and body extra care through meditation and talk therapy. These methods help manage pain and reduce stress that often comes with neuropathy.

Natural Therapies: Try gentle approaches like acupuncture and massage. Many people find relief through TENS therapy, which uses mild electrical pulses to ease pain.^[10]

Extra Support: Your healthcare team can recommend special shoes or supports to help you move safely and confidently. Physical therapy teaches you ways to work around numbness in your hands or feet.^[10]

Remember, these natural approaches work best when combined with supplements. Talk to your healthcare provider about which options might work best for your situation.

How Is Neuropathy Diagnosed?

Doctors diagnose neuropathy using a few simple steps:

Medical History: They ask about your symptoms, lifestyle, and any health conditions like diabetes or infections.

Physical Exam: The doctor checks your strength, reflexes, and sensation in affected areas.

Blood Tests: These can spot issues like vitamin deficiencies, diabetes, or thyroid problems that might cause nerve damage.

Nerve Tests:

• Electromyography(EMG): Electromyography measures how your muscles respond to electrical signals.^[11]
• Nerve conduction studies: Nerve conduction studies check how well signals travel through your nerves.^[11]

Imaging Tests: Scans like MRIs can look for nerve damage or other underlying problems.^[12]

Nerve or Skin Biopsy: In rare cases, a small sample of nerve or skin is tested to confirm the diagnosis.

Early diagnosis helps prevent further damage and starts the right treatment quickly and Supplements may help reduce discomfort and could even help you avoid more intensive treatments.

Key Mistakes to Avoid When Choosing Best Supplements For Nerve Pain

• Not researching the formula’s composition – Check the ingredients before buying the nerve supplements to ensure they support nerve health and benefit the body. Check out common ingredients like B vitamins, vitamin D, marshmallow root, alpha lipoic acid, corydalis powder, prickly pear, and passion flower herb, and try to avoid artificial or harmful substances that may cause adverse side effects.
• Not specifying your nerve health needs – The reason why you want to take supplements should lead you to the supplement you need to buy. For nerve pain or inflammation from diabetes, arthritis, or injury, try top nerve supplements. They support nerve function, ease pain, improve sleep, reduce stress, and may boost heart and brain health.
• Overlooking the product’s background – Choose your supplements from well-known, reputable, and trusted manufacturers who include only high-quality and effective ingredients in their formulations. Also, choose products that have numerous positive reviews because you will then be sure that it might work for you.

How Do Nerve Supplements Work?

Most nerve supplements work through their ingredients to support optimal nerve functions, reduce pain and inflammation, and improve mobility.

B vitamins work to nourish the nerves, promote the formation of red blood cells, enhance nerve communication, and support nerve functions.

Alpha lipoic acid works to improve conditions like diabetic peripheral neuropathy, regulate blood sugar levels, and improve insulin resistance.

Omega 3 fatty acids may improve sensorimotor functions in people who have had spinal cord injuries.

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Final Verdict

Neuropathy is a common condition that may cause dysfunction and damage to nerves. Nerve supplements have come out to help people deal with nerve pains and injury.

The supplements contain vitamins and herbs to help promote calmness, reduce stress and anxiety, alleviate pain, reduce inflammation, and enhance nerve recovery.

Certain ingredients may help boost energy levels, promote muscular regeneration, and protect nerves from oxidative stress. All you have to do is pick a supplement from our top picks and start enjoying its benefits.

Frequently Asked Questions