People take Elderberry supplements more than any other supplement to improve their body’s defenses against illness.
Supplements made from Sambucus plants contain antioxidants plus vitamins and minerals. Elderberry supplements protect your body against colds, flu, and harmful free radicals by strengthening your immune system.
People can choose from capsule pills, syrup drinks, and gummy sweets because these products adapt to various taste preferences and special diets. Regular consumption of elderberry supplements eases swelling in your body and builds your immunity against seasonal infections which are great health benefits.
Our Top Picks
Best Elderberry Supplement: WOWMD Black Sambucus Elderberry Extract
Best Elderberry Supplement for Adults: Gundry MD Mighty Reds
Best for Instant Results: ActivatedYou Vital Amino Essentials
Best Elderberry Supplements In 2025
WOWMD Black Sambucus Elderberry Extract – Best Elderberry Supplement
Our Rating
- Comfort 5/5
- Effectiveness 5/5
- Convenience 4.7/5
- Value 5/5
WOWMD Black Sambucus Elderberry Extract is a premium dietary supplement designed to support immune health and aid in weight management. Made with European elderberry extract it helps strengthen immunity, curb sugar cravings, and protect against oxidative stress.
This gluten-free, non-GMO formula provides essential antioxidants and nutrients to promote overall well-being. With easy-to-swallow capsules, it seamlessly fits into daily routines, making it a convenient way to enhance health and maintain balance.
Key Specs
- Form: Capsules
- Type: Dietary Supplement
- Brand: WOWMD
- Benefit: Boosts immunity, curbs sugar cravings, supports weight management, and provides antioxidant protection
- Active Ingredients: European Elderberry Extract (600 mg), Vitamin C, Zinc
- Dosage: 2 capsules daily with water, preferably in the morning
- Price: $44.10*
Pros & Cons of WOWMD Black Sambucus Elderberry Extract
Pros
- Supports immune health and weight management
- High-quality elderberry extract with Vitamin C & Zinc
- Gluten-free, non-GMO, and sugar-free
- 60-day money-back guarantee
- Manufactured in a GMP & FDA-certified facility
Cons
- May not work the same for everyone
- Needs consistent use for optimal results
WOWMD Black Sambucus Elderberry Extract Customer Reviews
Immune Support
It’s full of antioxidants as it contains elderberry, which is known to support immune health. I take these when I’m feeling a little under the weather. There is no after taste or smell. – Clare
Boost my immune system
I like these capsules because they help boost my immune system and aid in managing my weight. I will definitely purchase them again. – Wilson
Gundry MD Mighty Reds – Best Elderberry Supplement for Adults
Our Rating
- Comfort 5/5
- Effectiveness 5/5
- Convenience 4.7/5
- Value 5/5
Gundry MD Mighty Reds is a sugar-free, vegan gummy supplement packed with polyphenols, prebiotic fiber, and Vitamin D3 to support gut health, immune function, energy levels, and weight management.
Made with a blend of fruit and root extracts, it promotes digestion, boosts metabolism, and enhances overall wellness. These delicious gummies offer a convenient way to nourish your body with essential nutrients while satisfying your sweet cravings.
Key Specs
- Form: Gummies
- Type: Dietary Supplement
- Brand: Gundry MD
- Benefit: Supports digestion, energy, weight management, immune health, and joint flexibility
- Active Ingredients: Polyphenol Blend (elderberry, maqui berry, blueberry, cranberry, raspberry, pomegranate, turmeric, beet root), Prebiotic Blend (inulin syrup, Sukré™), Vitamin D3
- Dosage: 2 gummies per day
- Price: $49.95*
Pros & Cons of Gundry MD Mighty Reds
Pros
- Sugar-free and vegan-friendly
- Supports gut health and digestion
- Helps boost daily energy levels
- Contains powerful polyphenols for weight management
- Rich in antioxidants and prebiotic fiber
Cons
- Higher price point without a membership
- Results may vary among individuals
Gundry MD Mighty Reds Customer Reviews
Mighty Reds are great.
I’m starting g month 2 of Mighy Reds and they are great. Take one in late morning & one around 3pm. They give a boost of energy & make you feel energized. Just 2 gummies a day and it makes your body feel good. I look forward to seeing how the next 2 months go. Thank you Dr. Gundry – Jared
Mighty Reds
I have been using Mighty Reds for a little more than a month now. Not only are they easy to take but also very tasty! They do not have any funny after taste, no related heartburn, and they do not stick to my teeth! – Barb
ActivatedYou Vital Amino Essentials – Best for Instant Results
Our Rating
- Comfort 5/5
- Effectiveness 5/5
- Convenience 4.7/5
- Value 5/5
Vital Amino Essentials is a plant-based amino acid supplement designed to support energy, digestion, muscle maintenance, and immune function. It contains all nine essential amino acids, prebiotic fiber, phytonutrients, and additional key compounds for overall well-being.
This easy-to-mix, tropical citrus guava-flavored drink delivers powerful nutrients that help promote a healthy body composition, sustain energy levels, and aid in collagen production for better skin, hair, and joint health.
Key Specs
- Form: Powder
- Type: Dietary Supplement
- Brand: ActivatedYou
- Benefit: Supports energy, immune function, muscle recovery, digestion, and collagen production
- Active Ingredients: Amino9® Essential Amino Acid Blend, Eldermune™, PhytoServ™ Fruit Blend, Plant-Based D3 (VegD3®)
- Dosage: 1 scoop with 8 oz of water daily
- Price: $65.95*
Pros & Cons of ActivatedYou Vital Amino Essentials
Pros
- Contains all 9 essential amino acids
- Includes prebiotics and antioxidants for digestion and energy
- Vegan-friendly and free from artificial sweeteners
- Supports collagen production for skin, hair, and joint health
- 90-day money-back guarantee
Cons
- Results may vary among individuals
- Higher price compared to some alternatives
ActivatedYou Vital Amino Essentials Customer Reviews
I actually got this for my hisband , and he loves it . Feeling stronger , more energy and stamina. Great product. Thanks Activated You , you are changing our lives for the better and I love it. – Rebecca
My body feels better with Vital Amino Essentials.I ran out of the product and tried to replace it at my Natural Grocery Store. NOTHING COMPARES! This is a product I will always buy. The results are significant. – Melanie
What are Elderberry Supplements?
People acquire elderberry supplements from the Sambucus plant because it provides remarkable immune benefits.
Elderberry supplements have antioxidants like anthocyanins which shield cells from harm.
You can take the supplements through tasty gummies or capsules that include vitamin C and zinc for better immunity and well-being.
Why Is Elderberry Supplement Important?
Elderberry dietary supplements boost immune defenses and lessen cold and flu symptoms.
That is, users, can benefit from these supplements because their strong antioxidants fight cell damage, and vitamin C and zinc boost their overall wellness.
Taking these supplements helps to naturally strengthen your immune system.
How We Researched and Selected the Elderberry Supplements
Our testing procedure found the best-quality elderberry supplements on the market. Our team studied more than 70 user reviews alongside six health experts across 109 hours to identify the best elderberry supplements.
Our team studied elderberry products to ensure they had the highest concentration of immune-strengthening nutrients including vitamin C, zinc, and vitamin D.
Our selection process included third-party tests to verify product safety and effectiveness so that we could provide our customers only high-standard and risk-free products. Our research team analyzed product labels to find safe allergen ingredients while removing products that contain synthetic additives or unnecessary added sugars.
We tested supplements based on how well they provided quality at an affordable price. Alongside research, we tested multiple products to determine firsthand how they tasted and worked. Our team assessed product usability, packaging quality, and user experience alongside this information.
How To Choose the Best Elderberry Supplements?
You should research the quality and content of the product to match your needs in choosing the right elderberry supplement. Here are five key factors to consider:
1. Purity and Certification
Buy supplements that display USDA organic certification. These certifications ensure that the supplements contain no harmful ingredients and use the finest elderberries that preserve their natural vital nutrients.
2. Key Ingredients
Look for supplements using elderberry as the main ingredient and also possess other immune system-strengthening nutrients such as vitamin C, zinc, and vitamin D. The extra ingredients will fortify your immune system to deliver maximum benefits.
3. Prevent Harmful Additives
Scan supplement labels for supplements that contain natural elderberry and healthy nutrients that do not contain artificial flavors or other additives. Extra ingredients may reduce the health benefits a dietary supplement may be providing.
4. Third-Party Testing
Opt for supplements whose testing independent organizations do. The testing process protects your safety by ensuring the product meets exact standards to work as expected.
5. Form and Expert Guidance
Choose options that work best for you – take gummies for convenience or capsules for potency, and adjust the amount of syrups as necessary. Ask your doctor to verify if the supplement aligns with your health goals and medical condition when you have medical conditions or are taking medicines.
Common Ingredients Present in Elderberry Supplements
The ingredients composing elderberry supplements include elderberry extract, vitamin C, zinc, vitamin D, and some probiotics.
These ingredients work together to offer protection to the body against diseases and reduction of swelling as well as improvement of general health.
Elderberry Extract
According to the study published in the Plus One Journal, immune protection is a benefit given by elderberry supplements through the anthocyanins antioxidants that helps to combat oxidative stress.[1]
Vitamin D
According to Deanna M Minich, a well-recognized Certified Functional Medicine Practitioner (IFMCP), this supplement helps sustain the immune response by protecting the general health.[4]
Probiotics
Incorporating probiotics with elderberry protects gut health while making infections easier to handle for the immune system. These supplements work in checking the functioning of the immune system while also making infections much more manageable to deal with.[5]
Benefits of Elderberry Supplements
The key benefits to expect from these supplements include;
Reduces Inflammation: Elderberry’s antioxidants fight inflammation to help people manage joint pain and stay well.
Improves Respiratory Health: According to Dr Vanessa Piechotta a hematologist, elderberry can decrease respiratory infection symptoms by easing coughs and congestion, making breathing and clearing the airways simpler.[7]
Combats Oxidative Stress: Elderberry antioxidants fight free radicals to defend cells from harm through oxidative stress while lowering disease risks.[8]
Supports Gut Health: Some elderberry dietary supplements use probiotics that benefit your digestive system and gut bacteria for better immune protection.
Are Elderberry Supplements Safe to Use?
Elderberry supplements are generally safe for most people when properly used. However, product quality and choice of well-formulated products must be reasonable to eliminate possible risks.
Organic elderberry supplements are absolutely the safest form, free from harmful additions. Their use, in reasonable amounts, will benefit most human beings in the context of an improved immune system.
But even more importantly, it is advisable to seek recommendations from a healthcare provider before taking it, especially for an underlying health condition, pregnancy, breastfeeding, or when taking some form of medication.
Autoimmune status or immunosuppression requires cautiousness in its administration. Proper dosing and consideration of elderberry from reliable sources, which may mitigate most risks, can be achieved.
Potential Adverse Effects of Taking Elderberry Supplements
Most users have possibly safe elderberry supplements. However, it can lead to mild side effects also caused by gastro discomforts, headaches, and nausea, particularly in some users.
Moreover, unprocessed elderberry products in the form of raw elderberries contain cyanogenic glycosides, which can have a toxic impact and may lead to vomiting or diarrhea. Hence, you should never consume elderberries in raw form.
Anyone can have allergic reactions to the plant where elderberries come from, e.g., any other plant that is relevant to the Sambucus family.
Also, proper dosages should be followed, and a consultation with the health provider should be made before the administration, especially when one has pre-existing conditions.
Do Elderberry Supplements Work?
Elderberry supplementation has been studied extensively and holds potential benefits in supporting immunity and reducing the duration of colds and flu.
Studies have shown that elderberry augments the body’s defense mechanisms, especially when consumed along with other nutrients that could play a part in the natural boosting of the body’s immunity, such as vitamin C and zinc.
The latter properties of the supplement contribute to general health and well-being by helping with inflammation and oxidative stress, improving respiratory health. However, comprehensive research on its effectiveness needs to be done.
How do Elderberry Supplements work?
Elderberry supplements are nutritious for the immune system because of their high content of antioxidants, including anthocyanins, which protect the cells from damage by oxidative stress and reduce inflammation.
Antioxidants in elderberries help build the body’s immune system and can enhance the functioning of immune responses against infections, specifically viral infections like influenza.
Elderberry also possesses natural compounds that stimulate immune cells in order to enhance the functioning of immunity.
Most other elderberry supplements are often combined with vitamin C and zinc, which enhance the immune response and the capacity of the body to resist illnesses. This is very helpful, especially in a cold and flu season.
The active agents in the elderberries work to balance out the immune system, thereby bolstering it entirely.
When and How to Take Elderberry Supplements for Best Results?
For best effects, it is recommended that elderberry supplements be taken regularly. This should be done even before the start of cold or flu symptoms.
The usual dose often depends on the form (gummies, syrup, capsules) and brand, but it is commonly taken once or twice a day. Always follow the instructions given on the product label for accurate dosing.
Elderberry supplements may be taken with or without food. Take it regularly during cold and flu season. Consult with your healthcare provider to find out if the supplement aligns with your specific health needs.
Who Should Consider Using Elderberry Supplements?
Elderberry supplements are perfect for those who would like to maintain their immune system, especially in the cold and flu season.
Those who have frequent exposure to viruses, like healthcare workers, travelers, or parents of little children, might find it beneficial to take elderberry regularly.
The supplement is also helpful for someone who wants to reduce inflammation or support respiratory health. This also comes as an excellent option for individuals who desire a natural medicine that could reduce illness severity and duration.
Elderberry supplements are generally safe for most adults who practice preventive health measures aimed at keeping people healthy and helping build an individual’s immunity.
Who Should Stay Away from Elderberry Supplements?
People with autoimmune diseases, those taking immunosuppressive medications, and pregnant and breastfeeding women should not take any elderberry supplement unless permitted by a doctor due to a potential risk regarding the immune response or the baby/infant.
Why Trust Us?
All our recommendations are based on thorough research and consultation with experts to ensure accuracy and reliability.
We review products for quality, safety, and potency and emphasize third-party testing. We also look at user feedback and personally test the products.
This approach ensures that you get unbiased, well-informed advice to make safe, effective health decisions.
Final Verdict
Elderberry supplements provide natural protection for our immune health while reducing inflammation and fighting cold and flu symptoms.
Their dense antioxidant chemicals, like anthocyanins, shield us from cell damage while making our immune system stronger. Elderberry supplements regularly enhance your overall health defense against seasonal flu when taken daily.
Get your elderberry supplements from reputable suppliers who test for harmful additives and follow product label directions exactly.
Before starting elderberry supplements, talk to your doctor, especially when you have existing health problems or are expecting them.
Frequently Asked Questions
Q: Can elderberry supplements help prevent the flu?
A: Elderberry supplements show benefits for flu symptoms, yet they do not protect against flu infection. They show the most benefits when you start taking them at the beginning of your sickness.
Q: Does elderberry supplementation work for children as well as adults?
A: Parents should talk to their doctor about using elderberry supplements for children because proper dosages depend on age and medical status.
Q: How long does it take for elderberry supplements to work?
A: Many users notice symptom reduction between 24-48 hours after starting elderberry supplements when they take them during initial illness signs.
Q: Can I take elderberry supplements with other medications?
A: Elderberry supplements could affect how certain medicines work in your body. Tell your doctor first before you mix elderberry supplements with drugs you need to take to suppress your immune system or prevent blood clots.
Q: Are there any side effects from taking elderberry supplements?
A: Regular doses of elderberry supplements usually cause no problems, but certain users may notice gentle stomach upset or allergic symptoms. Follow the suggested medicine amount and talk to your doctor about the medical problems you encounter.
8 Sources
Health Insiders relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.
[1] Assessment of the role of anthocyanin standardized elderberry (Sambucus nigra) extract as an immune-stimulating nutraceutical of Nile tilapia, Oreochromis niloticus: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0279471
[2] Select Dietary Supplement Ingredients for Preserving and Protecting the Immune System in Healthy Individuals: A Systematic Review: https://doi.org/10.3390/nu14214604
[3] Zinc and immune function: the biological basis of altered resistance to infection: https://pubmed.ncbi.nlm.nih.gov/9701160/
[4] Is Melatonin the “Next Vitamin D”?: A Review of Emerging Science, Clinical Uses, Safety, and Dietary Supplements: https://www.mdpi.com/2072-6643/14/19/3934
[5] Reviewing the potential of probiotics, prebiotics and synbiotics: advancements in treatment of ulcerative colitis: https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2023.1268041/full
[6] Immune Activation by a Nutraceutical Blend: Rapid Increase in Immune-Modulating Cytokines, Followed by Induction of Anti-Inflammatory and Restorative Biomarkers: https://www.mdpi.com/1661-3821/4/1/3
[7] Elderberry for prevention and treatment of viral respiratory illnesses: a systematic review: https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-021-03283-5
[8] Genus Sambucus: Exploring Its Potential as a Functional Food Ingredient with Neuroprotective Properties Mediated by Antioxidant and Anti-Inflammatory Mechanisms: https://www.mdpi.com/1422-0067/25/14/7843
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Health Insiders Team
The Health Insiders Team takes pride in bringing you the latest in nutritional research, skincare, healthy living, and wellness hacks. [Read Full Bio]