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Supplements containing conjugated linoleic acid can be an effective means of weight loss for many people. In the following review, we highlight the best conjugated linoleic supplements in 2025.
Trying to lose weight via diet and exercise alone can be very challenging. That’s because the body needs certain nutrients to burn fat effectively. And you may not be getting these kinds of nutrients in your normal diet.
Areas of the body that accumulate visceral fat can also be very problematic when you are trying to lose weight. That’s why supplements containing nutrients like conjugated linoleic acid (or CLA for short) can be very helpful.
But CLA supplements often contain other ingredients so it can be difficult to figure out which ones are worthwhile and which ones should be avoided. So in the following article, we will be talking about what you need to know about conjugated linoleic acid, how it may affect your body and we will also be detailing some of the CLA supplements you should check out.
What is Conjugated Linoleic Acid?
Conjugated linoleic acid is a type of natural fatty acid that you can ingest by eating beef and dairy products. The reason CLA is included in weight loss supplements is because it has exhibited the ability to slow the fat-making process of the body and speed up the process by which the body breaks down fat. [1]
CLA is certainly a notable substance when you’re talking about weight loss because it actually helps the body get rid of visceral fat – the kind of fat that is visible on the body and makes the most impact on your physique.
CLA is a naturally-occuring fatty acid so it is safe for most healthy adults. CLA supplements typically use a concentrated form of CLA at an ample dosage to accelerate its effects on the body.
Our Top Picks of 2025
Most Effective CLA Supplement: Liposet
Read The ReviewsBest CLA Supplement for Healthy Body Composition: VitaBalance CLA 2000
Best CLA Supplement for Healthy Weight Loss: Puravive
Best CLA Supplement for Bodybuilding: BulkSupplements CLA
Best CLA Supplement Overall: GNC Total Lean CLA
The Best Conjugated Linoleic Acid Supplements in 2025
Liposet – Most Effective CLA Supplement
*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
Liposet is a natural weight loss supplement that pairs conjugated linoleic acid with glucomannan to spur weight loss while at the same time improving your digestive functions.
Included in the formula is a 4 mushroom blend which helps prevent inflammation and may have cognitive benefits as well. Liposet can help your body burn fat and allow you to derive more nutrients and energy from the food you eat.
Key Specs
- Form: Capsule
- Type: Weight loss
- Brand: Liposet
- Active Ingredients: Conjugated Linoleic Acid (CLA), Glucomannan, 4 Mushroom Blend, Silica
- Benefit: Helps the body burn fat, improves digestive functions, helps reduce food cravings
- Dosage: 1 capsule about 45 minutes before every meal
- Price: $49*
Pros & Cons of Liposet
Pros
- The formula is natural
- Helps reduce unhealthy food cravings
- Cognitive benefits
- Antioxidant defense
Cons
- It may sell out quickly
Liposet Customer Reviews
It Works like Magic
This stuff works! Leaves me feeling full tummied and not wanting to continue consumption- lots of energy – and also have noticed my hair strengthening and growing! Grab this product and you will lose some lbs curb some hunger and lose some inches off the pant sizes! – Brittany LaFond
Arrived on time and does work great!
Suppresses my appetite if taken as directed, great jump start to diet. I would recommend to try it before getting skinny fiber. – Gigi
VitaBalance CLA 2000 – Best CLA Supplement for Healthy Body Composition
*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
As the name implies, there is a 2000mg dose of CLA in every serving of VitaBalance CLA 2000. This may make it a very effective supplement for body-builders because at this dosage, CLA can also help you build lean muscle. This supplement may also help to increase physical endurance.
Key Specs
- Form: Softgels
- Type: Weight loss
- Brand: VitaBalance
- Active Ingredients: CLA
- Benefit: Helps the body burn fat and can help build lean muscle
- Dosage: 2 softgels daily
- Price: $24.95*
Pros & Cons of VitaBalance CLA 2000
Pros
- Good for bodybuilders
- Enhances physical endurance
- Safe formula
- Improves physique
Cons
- Results may vary
VitaBalance CLA 2000 Customer Reviews
Beach ready
I fit perfectly into a swimsuit I bought last month which was too tight. Seems to be working, starting my second bottle now. – Caitlyn
Pleased with the result.
I’ve been taking this for about a month and I’m satisfied with the results. Happy to recommend CLA 2000. – Eva
Puravive – Best CLA Supplement for Healthy Weight Loss
*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
Puravive is an excellent health and wellness supplement because aside from weight loss, it can also improve heart health and strengthen the immune system. Puravive may produce rapid results for your weight loss efforts because the formula helps the body break down fat and prevent fat deposition.
Key Specs
- Form: Capsule
- Type: Weight loss
- Brand: Puravive
- Benefit: Improves physique and supports cardiovascular health
- Active Ingredients: Holy basil, kudzu, propolis
- Dosage: 1 capsule a day with water
- Price: $59*
Pros & Cons of Puravive
Pros
- Natural formula
- Supports overall health
- Good customer reviews
- Fast weight loss
Cons
- Shipping may be delayed
Puravive Customer Reviews
Went down 3 dress sizes!!
I never used to leave the house, worried about not fitting into chairs or public transport. Now after trying Puravive I’m down 35 lbs! I feel and look amazing. My energy levels are through the roof and I regularly use the bus and try on slim clothes and shop in the mall stress free. Thank you so much! Puravive – Barbara M.
26lbs lighter so far…
I was so embarrassed when my son grabbed my belly and asked, Daddy why is your tummy so squishy. I had to do something, and when I saw the Puravive video and verified the research I had to try it out. I’m down 26 lbs and it keeps melting off! My snoring has disappeared. I feel fitter and happier than I did in my 30s! – Clifton B.
BulkSupplements CLA – Best CLA Supplement for Bodybuilding
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*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
Conjugated Linoleic Acid (CLA) Softgels from BulkSupplements is a dietary supplement sourced from safflower oil. Each serving consists of 2 softgels, totaling 2000mg, with each softgel containing 1000mg of CLA. Bodybuilders commonly use it to aid in muscle growth, metabolism support, and as a fat burner.
Key Specs
- Form: Softgels
- Type: Supplement
- Benefit: Supports weight management, metabolic health, heart health, immune support, and provides antioxidant effects
- Brand: BulkSupplements
- Active Ingredients: Conjugated Linoleic Acid (CLA) sourced from safflower oil
- Dosage: Take 2 softgels daily
- Price: $18.96 *
BulkSupplements CLA Pros & Cons
Pros
- Supports weight management and metabolism
- Potential benefits for heart health and immune support
- Contains antioxidant properties
- Convenient softgel form for easy consumption
Cons
- May not be suitable for individuals with certain medical conditions or allergies
- Requires consistent daily intake for optimal benefits
- Potential side effects or interactions with other medications should be considered
GNC Total Lean CLA – Best CLA Supplement Overall
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*All the prices listed here are as they appear on their websites and are subject to change.
Our Rating
The product from GNC, “Total lean CLA Conjugated Linoleic Acid,” is a dietary supplement designed to support fat metabolism without stimulants.
The supplement is scientifically shown to help improve lean muscle mass, body composition, and fuel energy and fat metabolism. It delivers 4000mg of CLA per day, with each softgel containing 1000mg of CLA.
Key Specs
- Form: Capsules
- Type: Supplement
- Benefit: Improves body composition, lean muscle tone, and supports metabolism and energy production
- Brand: GNC Total Lean
- Active Ingredients: Conjugated Linoleic Acid (CLA) sourced from safflower oil, Gelatin, Glycerin
- Dosage: 2 softgel capsules twice daily with meals
- Price: $44.99*
GNC Total Lean CLA Pros & Cons
Pros
- Supports body composition improvement and lean muscle tone
- Stimulant-free energy support
- Enhances metabolism and fat metabolism
- Caffeine-free formula
- Gluten-free
Cons
- May not be suitable for individuals sensitive to gelatin or glycerin
- Potential side effects like gastrointestinal discomfort in some individuals
- Individual results may vary
GNC Total Lean CLA Customer Reviews
Product works
With exercise and right diet the product will give you results. You will use restroom frequently – Fran
Just normal
Good deal. Nothing to rave about it’s efficacy. – David Lau
What Are the Ideal Ingredients for Weight Loss Supplements?
Glucomannan
Glucomannan is a natural fiber that helps slow down the stomach’s emptying process. Glucomannan can also promote weight loss by increasing satiety after a meal.[3]
What Are the Benefits of Taking CLA Supplements?
There are many benefits to taking these supplements which includes:
Improved Digestion – Some CLA supplements can also promote bowel movement regularity and digestive health.
Increased Fat-Burning – These supplements are excellent complements to an exercise regimen because they intensify fat-burning.
How Effective Are CLA Supplements for Weight Loss?
Conjugated linoleic acid has a very specific type of effect on the body. Researchers have found that it can reduce body fat by up to 60% as we see in the following National Institutes of Health study quote:[5]
The dramatic effect CLA has on adiposity has been studied for the past 20 years. Initial studies in male and female ICR mice showed that a mixed CLA-supplemented chow diet promoted fat loss by 60% over 30 days.
The study goes on to mention that CLA appears to speed up the fat oxidation processes of the body. This means that taking CLA can improve your body’s ability to burn fat which will have a considerable impact on your body.
There have also been studies that suggest that taking CLA can benefit you if you live a mostly sedentary lifestyle. The study reported that even for test subjects who didn’t regularly exercise, CLA still helped prevent fat deposition.[6]
So if you don’t have a lot of time to go to the gym and exercise, conjugated linoleic acid supplements can help keep you fit.
How Did We Rank the Best CLA Supplements?
We thoroughly researched some of the best-selling CLA weight loss supplements. This included looking at the formulas, analyzing reviews from confirmed customers, looking into the manufacturer of these supplements and what they can do for the average consumer.
We also went over scientific studies from leading authorities on the ingredients in these products. Our goal is to present the consumer with valuable information that will help them make the best decision for their weight loss goals.
Final Verdict
Yes, it is possible to lose weight without taking a CLA supplement. But it will be a lot harder for you to reach your weight loss goals without them. CLA supplements can also make a visible difference in how you look in a short amount of time.
The products we highlighted in the above list represent some of the best and most beneficial CLA supplements currently on the market. Use the information we have provided to choose a CLA supplement that will help you achieve your weight loss goals.
Frequently Asked Questions
Q: Are CLA supplements FDA-approved?
A: The FDA does not actually regulate natural supplements like conjugated linoleic acid supplements.
Q: How long does it take for CLA Supplements to work?
A: Everyone’s body is different so they will react to CLA supplements differently. Result times may vary.
Q: Are CLA supplements safe to use?
A: CLA is a natural fatty acid that is well-tolerated by adult users. But you should always talk to a doctor before beginning any type of supplements regimen.
Q: Can you take CLA supplements without working out?
A: You can but the results are likely to come a lot slower. They may also be less pronounced if you don’t exercise.
Q: Are there any substances or supplements that should not be combined with CLA?
A: Dr. Matthew Casavant says, While CLA is generally safe, I would advise against combining it with blood thinners like warfarin, as it may increase the risk of bleeding. I also would not recommend combining CLA with diabetes medications, as it can alter blood sugar levels.
6 Sources
Health Insiders relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.
[1] Conjugated Linoleic Acid Effects on Cancer, Obesity, and Atherosclerosis: A Review of Pre-Clinical and Human Trials with Current Perspectives: https://pmc.ncbi.nlm.nih.gov/articles/PMC6413010/
[2] The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials: https://pubmed.ncbi.nlm.nih.gov/30335479/
[3] Safety and Efficacy of Glucomannan for Weight Loss in Overweight and Moderately Obese Adults: https://pmc.ncbi.nlm.nih.gov/articles/PMC3892933/
[4] Dietary capsaicin and its anti-obesity potency: from mechanism to clinical implications: https://pmc.ncbi.nlm.nih.gov/articles/PMC5426284/
[5] Conjugated Linoleic Acid Effects on Cancer, Obesity, and Atherosclerosis: A Review of Pre-Clinical and Human Trials with Current Perspectives: https://pmc.ncbi.nlm.nih.gov/articles/PMC6413010/
[6] Pros and cons of CLA consumption: an insight from clinical evidences: https://pmc.ncbi.nlm.nih.gov/articles/PMC4429457/
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Health Insiders Team
The Health Insiders Team takes pride in bringing you the latest in nutritional research, skincare, healthy living, and wellness hacks. [Read Full Bio]
Brittany Ferri, MS, OTRL, CLT
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